CDC’s Advanced Molecular Detection (AMD) initiative aims to improve the identification and characterization of infectious diseases by increasing critical next generation sequencing (NGS) and bioinformatics capacities at CDC and at state and local health departments.

Since 2013, APHL has worked with CDC and other partners to characterize current NGS capability and capacity, develop a strong AMD workforce and deploy NGS technologies to public health laboratories. Review the CDC/APHL Advanced Molecular Detection Strategic Map, 2015-2017.

Characterizing Capacity

APHL regularly surveys public health laboratories to identify improvements in AMD capabilities, pinpoint areas that still need improvement and identify mitigation strategies.    

Building the AMD Workforce

APHL has administered the APHL-CDC Bioinformatics Fellowship since its launch in 2013. The fellowship aims to train and prepare bioinformaticians to apply their expertise within public health and to design tools that will aid existing public health personnel in the use of bioinformatics.

APHL is offering a four-part webinar series free of charge to state and local health department staff. Continuing education credits are available.
Webinar 1: “An Overview of CDC’s Advanced Molecular Detection Initiative
Webinar 2: “Bioinformatics in Public Health Laboratories” 
Webinar 3: “Whole Genome Sequencing of Bacterial Pathogens
Webinar 4: June 15, Registration information coming soon

Deploying Technology

APHL works closely with CDC and public health laboratories to build AMD capacity to improve the detection and surveillance of particular pathogens. Through the organization of training opportunities, facilitation of technical assistance and management of proficiency checks, APHL has assisted with the transfer of AMD technologies in several key program areas.

More Information

CDC Advanced Molecular Detection

APHL Stories from the Field, Influenza

APHL Stories from the Field, Legionella